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Using interictal seizure-free EEG data to recognise patients with epilepsy based on machine learning of brain functional connectivity
Most seizures in adults with epilepsy occur rather infrequently and as a result, the interictal EEG plays a crucial role in the diagnosis and classification of epilepsy. However, empirical interpretation, of a first EEG in adult patients, has a very low sensitivity ranging between 29-55 seizure-free EEG epochs, far beyond the observational capabilities of any specialised physician in this field. Unlike most of the existing works focusing on either seizure data or single-variate method, we introduce a multi-variate method to characterise sensor level brain functional connectivity from interictal EEG data to identify patients with generalised epilepsy. A total of 9 connectivity features based on 5 different measures in time, frequency and time frequency domains have been tested. The solution has been validated by the K-Nearest Neighbour algorithm, classifying an epilepsy group (EG) vs healthy controls (HC) and subsequently with another cohort of patients characterised by non-epileptic attacks (NEAD), a psychogenic type of disorder. A high classification accuracy (97 significant spatio temporal deficits in the frontocentral areas in the beta frequency band. For EG vs NEAD, the classification accuracy was only about 73 which might be a reflection of the well-described coexistence of NEAD with epileptic attacks. Our work demonstrates that seizure-free interictal EEG data can be used to accurately classify patients with generalised epilepsy from HC and that more systematic work is required in this direction aiming to produce a clinically useful diagnostic method.
Recognition of visual-related non-driving activities using a dual-camera monitoring system
For a Level 3 automated vehicle, according to the SAE International Automation Levels definition (J3016), the identification of non-driving activities (NDAs) that the driver is engaging with is of great importance in the design of an intelligent take-over interface. Much of the existing literature focuses on the driver take-over strategy with associated Human-Machine Interaction design. This paper proposes a dual-camera based framework to identify and track NDAs that require visual attention. This is achieved by mapping the driver’s gaze using a nonlinear system identification approach, on the object scene, recognised by a deep learning algorithm. A novel gaze-based region of interest (ROI) selection module is introduced and contributes about a 30